Merck KGaA will hold the responsibility for executing the preclinical and clinical research of the ADC programmes. Credit: 漏 Merck KGaA, Darmstadt, Germany.

Caris Life Sciences’ research division, Caris Discovery, has entered a multi-year strategic collaboration with KGaA (Merck) to discover new cancer targets and expedite the development of antibody-drug conjugates (ADCs) for cancer.

Merck will gain the sole worldwide global licence for developing, producing and marketing ADC therapeutics for specific targets.

Go deeper with GlobalData

  • ReportsLogo

  • ReportsLogo

Data Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

Merck will make an upfront payment and provide research funding to Caris.

Caris is entitled to receive $1.4bn in potential milestone payments on meeting discovery, development, regulatory and sales-based goals, apart from sales-based tiered royalties.

Caris Discovery utilises the extensive molecular profiling capabilities of Caris for the discovery of new targets that traditional methods may miss.

Caris Discovery focuses on finding and validating new therapeutic targets for its biopharma partners to create advanced oncology treatments.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile 鈥� free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

The company will combine its ADAPT biotargeting system, a patient tissue repository, advanced AI and machine learning technologies, and a 59,000ft虏 discovery research laboratory.

Merck will hold an option to pursue targets discovered and validated by Caris.

Merck will execute the preclinical and clinical research and will develop and market drug candidates that emerge from these programmes.

Caris chief business officer Brian Lamon stated: 鈥淲e are thrilled to join forces with Merck to discover targets with the first-in-class potential to advance the next wave of transformational ADC therapeutics.

鈥淭his partnership adds to our portfolio of external pipeline programmes and is a strong validation of our highly differentiated, orthogonal multi-omics approach to discovering truly novel targets that may be harnessed to eradicate tumours.鈥�

In March 2023, Merck聽announced a 鈧�300m investment to establish a new bioprocessing production centre in Daejeon, South Korea.